Abstract

SANCHEZ SEGURA, Miriam C. et al. Congenital hypogammaglobulinemia associated with granulocyte disorders.: A case presentation. Rev Cubana Hematol Inmunol Hemoter [online]. 2009, vol.25, n.3, pp. 0-0. ISSN 1561-2996.

This is the case of a child aged 11 months with a history of systemic sepsis from Pseudomona aeruginosa at 5 months, neutropenia, leucopenia, sepsis-associated anemia and from then, recurrent acute respiratory infections of the high respiratory tract, allergic manifestations and furunculosis from pseudomona. Immunologic study conducted showed a decreased figure of IgG with a light increase of CD4+ cooperative-IgM of T cells. Also, we found the presence of neutropenia and marked defect of phagocytosis. We made the diagnosis of granulocyte-associate congenital hypogammaglobulinemia. The patient was treated with human gamma globulin by intramuscular route, transference factor and immunoferon, with an obvious improvement.

Keywords : Hypogammaglobulinemia; primary immunodeficiency; neutropenia; phagocytosis.

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