Abstract

DEL VALLE PEREZ, Lázaro O. et al. In vitro effect of a solution of Zingiber officinale Rosc. (Ginger) on the response of human lymphocytes from healthy donors and patients with cellular immunodeficiency. Rev Cubana Hematol Inmunol Hemoter [online]. 2010, vol.26, n.3, pp. 216-222. ISSN 1561-2996.

The Zingiber officinale Rosc (ginger) is a species used by man to different purposes. The in vitro effect of a aqueous solution from the rhizome of this plant on the lymphocytes of 30 volunteer blood donors and of 30 patients diagnosed with cellular immunodeficiency was studied by the lymphoblastic transformation test using tritiated thymidine, the technique of the rosette active formation and the immunocytochemical ultramicromethod (UMICIQ). There were not statistically significant differences among the experimental conditions with and without ginger with dilutions from 1:2 to 1:128 in the lymphoblastic transformation test. In the active rosette and in markers of the HLA-DR and CD25 activation there weren't statistically significant differences among lymphocytes without ginger and those cultured with a dilution 1:128 for healthy donors and for the patients.

Keywords : Ginger; Zingiber officinale Rosc; lymphoblastic transformation; active rosette; UMICIQ; activation markers.

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