Abstract

MACIAS ABRAHAM, Consuelo. Histocompatibility: past, present and future. Rev Cubana Hematol Inmunol Hemoter [online]. 2015, vol.31, n.1, pp. 53-58. ISSN 1561-2996.

Histocompatibility is the area of Immunology for the study or typing of antigens expressed in the surface of leukocytes, of high polymorfirsm, genetically determined by different allelic variants, implied in organs and tissues reject due to its high level of immunogenicity.  The development of Immunology in Cuba since the 1970´s has allowed the gradual introduction of technologies that made it possible to type these antigens and the development of hematopoietic and kidney transplants in our country.  The use of molecular biology in this area has made it possible the most precise identification of existing and new antigenic variants previously not known, which have contributed to enlarge new possibilities for hematopoietic transplant to non related donors and with blood cord cells, which increased the options for cure in different diseases.

Keywords : histocompatibility; transplant; immunology; hematology.

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