Abstract

MORALES, Maydelin Miguel  and  AGRAMONTE LLANES, Olga M. Proteinuria in monoclonal gammopathies. Rev Cubana Hematol Inmunol Hemoter [online]. 2016, vol.32, n.2, pp. 0-0. ISSN 1561-2996.

The presence of protein in urine is called proteinuria in adults is clinically defined by a urinary excretion of more than 150 mg in 24 hours and proteins occurs by a change in the glomerular filtration barrier, which allows the escape of proteins in urine. Proteinuria is common in various diseases, particularly monoclonal gammopathies. The criteria for diagnosis of these entities include the presence of abnormal plasma cells in the bone marrow, a monoclonal protein increased serum, a monoclonal protein in urine or osteolytic lesions. For diagnosis, evaluation and treatment monitoring of monoclonal gammopathies,  electrophoretic studies proteins plasma or serum and urinary proteinograms technique that allows separation of proteins based on their differential migration when subjected to an electric field is performed.

Keywords : proteinuria; gammopathy; multiple mieloma; renal disease.

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