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Revista Cubana de Hematología, Inmunología y Hemoterapia
On-line version ISSN 1561-2996
Abstract
LA ROSA HERNANDEZ, Deyanira; SANCHEZ CASTANEDA, Niurka; VILLA JIMENEZ, Oscar and GOMEZ CABEZAS, Enrique J. Common variable immunodeficiency and selective IgA deficiency in celiac disease patients. Rev Cubana Hematol Inmunol Hemoter [online]. 2016, vol.32, n.3, pp. 394-402. ISSN 1561-2996.
Celiac disease (CD) is an autoimmune gastrointestinal disease very often associated with Primary Immunodeficiencies (PID) as selective IgA deficiency and variable immunodeficiency common. About the link between celiac disease IDP, two female patients diagnosed as celiac patients with different forms of presentation and varying commitment immunonutritional presented. Low levels of immunoglobulin G (IgG) and absence of immunoglobulin A (IgA) were the main humoral findings recorded, no commitment of B and T cells, according to the quantification of lymphoid subpopulations by flow cytometry. Nutritional and immunological intervention allowed remission of clinical manifestations and satisfactory outcome in both cases.
Keywords : celiac disease; selective IgA deficiency; common variable immunodeficiency.