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Revista Cubana de Hematología, Inmunología y Hemoterapia
On-line version ISSN 1561-2996
Abstract
MARTINEZ AVILA, Daniel Ricardo et al. SMILE in relapsed extranodal NK / T cell lymphoma. Rev Cubana Hematol Inmunol Hemoter [online]. 2019, vol.35, n.3 Epub Nov 30, 2019. ISSN 1561-2996.
Introduction:
Extranodal lymphoma of NK / T cells, nasal type is an aggressive variety that occurs most frequently in East Asia and Latin America. The SMILE treatment regimen, based on dexamethasone, methotrexate, ifosfamide, L-asparaginase and etoposide, showed adequate objective response rates in phase 1/2 studies.
Objective:
to present the first report of the application of the SMILE protocol in Cuba.
Case presentation
: 47-year-old white patient who presented early relapse of extranodal lymphoma of nasal NK / T cells in soft parts of the left anterior wall of the thorax. He received SMILE chemotherapy for 4 cycles and the evaluation at the end of the treatment showed that there was a complete response of the disease.
Keywords : extranodal lymphoma; NK / T cells; ENKTL-NT; SMILE protocol; angiocentric T-cell lymphoma.
