Abstract

HARRIS RICARDO, Jonathan; DIAZ CABALLERO, Antonio José  and  FORTICH MESA, Natalia. Oral lesions associated with antiretroviral treatment and viral load in HIV/AIDS patients. Rev Cubana Invest Bioméd [online]. 2013, vol.32, n.3, pp. 284-292. ISSN 0864-0300.

Objective: determine the association between oral manifestations and antiretroviral therapy and viral load in HIV/AIDS patients. Methods: a cross-sectional study was conducted of a population of 166 patients in Cartagena, Colombia. Data collection followed the recommendations of the Center for the exchange of criteria on oral conditions related to HIV infection, and the parameters for the clinical diagnosis of oral manifestations associated with HIV infection established by the WHO (World Health Organization) Collaborating Center for oral checkups. Viral load and antiretroviral therapy data were obtained from medical records. Results: 66.7% of the patients affected were men and 33.3% were women. Mean age was 36.1 years. Prevalence of oral manifestations associated with HIV was 59.5%, and candidiasis was the most common with 35.5%. Patients under monotherapy presented fewer oral manifestations (OR: 0.20; CI: 0.00-0.96 (P<0.02)). Conclusion: Patients under antiretroviral drug monotherapy presented fewer oral lesions than those under bitherapy.

Keywords : antiretroviral drug therapy; viral load; oral candidiasis; HIV infection.

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