Abstract

CRUZ GOMEZ, Elizabeth; GARCIA GARRIDO, Rosa Mireya; LAMOTTE CASTILLO, José A  and  FERNANDEZ ARIAS, Karelis. Determination of hematochemical parameters in HIV/AIDS patients treated with antiretrovirals. Rev Cubana Invest Bioméd [online]. 2014, vol.33, n.2, pp. 102-109. ISSN 0864-0300.

Introduction: Antiretroviral therapy has had a great impact on the quality of life of people living with HIV/AIDS, but these drugs require strict surveillance due to their toxic effects. Methods: A study was conducted of 50 HIV/AIDS patients under antiretroviral treatment cared for at Dr. Juan Bruno Zayas hospital from May to September 2011. Determination was performed of variations in hematochemical parameters, including lipid profiles and hematological and renal studies. Results: Most alterations in lipids were found in patients from the Rescue scheme. All schemes showed alterations in total proteins and microalbuminuria, whereas most patients in Schemes 4, 1 and Rescue had anemia. The patients studied presented moderate alterations of the parameters analyzed. Conclusions: Toxicity of the treatments applied is below that reported by other studies.

Keywords : antiretroviral therapy; hematobiochemical parameters; toxicity.

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