Abstract

ESPINOSA SANTISTEBAN, Iecienia; PEREZ RAMOS, Aydelin; BARBER FOX, Maria Ofelia  and  GARCIA SARDINAS, Juliett. Plasma creatinine, glomerular filtration and blood pressure in children with low birth weight due to intrauterine growth retardation. Rev Cubana Invest Bioméd [online]. 2014, vol.33, n.2, pp. 161-167. ISSN 0864-0300.

Introduction: Low birth weight due to intrauterine growth retardation (IUGR) may induce renal function modifications leading to arterial hypertension. Objective: Assess blood pressure in normotensive children with a personal history of low birth weight due to IUGR. Methods: A study was conducted of plasma creatinine, glomerular filtration and blood pressure in 19 normotensive children aged 4-5 years with a history of low birth weight due to IUGR (Group 1: IUGR) and their controls (Group 2: Controls). Results: A lower plasma creatinine concentration was found in Group 1 (0.691 vs. 0.751) with p=0.001*, whereas similar values were found for blood pressure (80.0 vs. 78.5) and glomerular filtration intensity (86.1 vs. 83.4) with p<0.05. Conclusions: Renal function modifications occurring before the study period may not be discarded.

Keywords : intrauterine growth retardation; hypertension; kidney.

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