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Nucleus
Print version ISSN 0864-084X
Abstract
CRUZ ARENCIBIA, Jorge; GARCIA RODRIGUEZ, Enrique; SAGARRA VERANES, Marta and MORIN ZORRILLA, José. Radiopharmaceuticals in radiosynoviorthesis. Nucleus [online]. 2010, n.47, pp. 3-7. ISSN 0864-084X.
ABSTRACT The radiosynoviorthesis is a procedure of metabolic radiotherapy, consisting in the intrarticular injection of a radiopharmaceutical with a beta emitting radionuclide for the treatment of chronic sinovitis, frecuently present in reumatoid arthritis, haemophilia and other systemic diseases. As this is a safe, effective and a relatively low-cost procedure, It is ordinarily used in Europe, USA and in some Latin American countries. The existing commercial products are based on ,
,
and
, although research is carried out on the use of
,
, among others radionuclides. In Cuba a suspension of Chromium Phosphate (III) labeled with
, is on trial. The above-mentioned suspension has enough characteristics to become an efficient and safe product in practice.
Keywords : radiopharmaceuticals; radioisotopes; radionuclide kinetics; bone joints; rheumatic diseases; clinical trials.