My SciELO
Services on Demand
Article
Indicators
Cited by SciELO
Related links
Similars in SciELO
Share
Revista Cubana de Ortopedia y Traumatología
On-line version ISSN 1561-3100
Abstract
TABARES NEYRA, Horacio and DIAZ QUESADA, Juan Miguel. Relationship between disc degeneration, lumbar pain and stability: Disc degeneration. Rev Cubana Ortop Traumatol [online]. 2015, vol.29, n.2, pp. 0-0. ISSN 1561-3100.
Aging and degeneration result in changes in the spine; the discs lose their ability to fulfill their functions. A critical review on the intervertebral disc degeneration, pain and stability of the lumbar spine was carried out for which progress in the understanding of disc degeneration process, the influence factors and its cellular processes, as well as the most widely used pathologic classification and its reflection in resonance images were reviewed. The disk cell changes occur through six processes; which causes biochemical changes in the extracellular matrix and loss of function. Cells play the major role in biological and biochemical changes of intervertebral disc degeneration. Genetic predisposition, nutritional and oxygen supply and mechanical stress are involved as other factors in this process, in addition to aging.
Keywords : disc degeneration; cells; genetic predisposition; mechanical stress.