Abstract

AMBROS GOMEZ, Itahimy et al. Association of ocular pulse amplitude and intraocular pressure and effectiveness of the hypotensive treatment. Rev Cubana Oftalmol [online]. 2010, vol.23, n.1, pp. 136-144. ISSN 1561-3070.

OBJECTIVES: To determine the association of the ocular pulse amplitude and the ocular pressure in patients with primary open angle glaucoma by groups under treatment; to evaluate the ocular pulse amplitude as a means to assess the effectiveness of anti-hypertensive ocular therapy and to define correlation between central corneal thickness/ocular pressure, and corneal thickness and pulse amplitude using the dynamic contour tonometer. METHODS: Ninety patients aged over 15 years, recently diagnosed with primary open angle glaucoma and still untreated, were studied. They were randomly included in three study groups according to the indicated drug, that is, Group I- 0,5 % Timolol, Group II- 0,2 % Travoprost (Travatan) and Group III- 2 % Dorzolamide (Trusopt). Their central corneal thickness was measured by pachymetry prior to the treatment, and one week, one month and 3 months later at the the glaucoma service at "Ramón Pando Ferrer" Cuban Institute of Ophthalmology (December 2006-May 2007). Also the variables intraocular pressure and ocular pulse amplitude were taken. RESULTS: It was found that pulse amplitude decreases as the intraocular pressure goes down; higher decline in pressure and pulse amplitude existed in group under Travoprost treatment where the correlation of both variables was better. No correlation was observed between central corneal thickness and intraocular pressure; similarly the corneal thickness and the pulse amplitude did not correlate. CONCLUSIONS: Monitoring the pressure and the pulse amplitude may be effective to find out the effect of the ocular hypertensive therapy.

Keywords : Dynamic contour tonometry; ocular pulse amplitude.

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