Abstract

CACERES TOLEDO, María; MARQUEZ FERNANDEZ, Melba  and  CACERES TOLEDO, Odalys. Botulinum toxin type A versus surgery in the eyelid retraction of thyroid orbitopathy. Rev Cubana Oftalmol [online]. 2010, vol.23, n.2, pp. 241-248. ISSN 1561-3070.

INTRODUCTION: Eyelid retraction is the most frequent sign of Thyroid Orbitopathy (TO). The objective of this study was to evaluate the results of Botulínum Toxin type A (BTA) in its correction and to compare them with those from the surgery in cases with the same clinical severity of the retraction. METHODS: A prospective and descriptive study was performed in 24 patients with eyelid retraction from December 2008 to February 2009; they were divided into two groups, being the first treated with botulinum toxin type A and the second with surgical procedure RESULTS: The results with the BTA were satisfactory in 8 cases (67 %), with slight and moderate retraction, 6 of them were in the congestive stage of the TO. The treatment was unsatisfactory in 4 cases with moderate and severe retraction in the chronic stage and fibrosis of lower rectus. The results of the surgery were satisfactory in the 10 operated patients (83.3 %). The number of retraction millimetres (mm) before the BTA injection and its reduction in the day 7^th, 45^th and 90^th were shown. There were no significant differences in the number of corrected retraction milimeters between both methods in similar cases from the clinical viewpoint. CONCLUSIONS: The botulinum toxin A is a therapeutic alternative for the slight and moderate eyelid retraction in the congestive period of the thyroid orbitopathy. Both treatments managed to correct the same number of retraction milimeters, in cases with similar degree of damage.

Keywords : Eyelid retraction; botulinum toxin type A; surgery.

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