Abstract

GONZALEZ PENA, Odalys et al. Maculopathy from use of chloroquine. Rev Cubana Oftalmol [online]. 2010, vol.23, n.2, pp. 444-449. ISSN 1561-3070.

Chloroquine toxicity depends on the dose. A cumulative dose of under 100 g of chloroquine or a length of treatment for less than one year is rarely associated to any retinal lesion. The toxicity risk significantly increases with the cumulative dose over 300 g (250 g/day for three years). The case of a female patient with a history of lupus erythematosus for 17 years was presented. She was treated with chloroquine (one 250 mg every day) for 15 years. The main symptom was slow and progressive reduction of visual acuity experienced for 2 years; a complete ophthalmologic exam and other supplementary tests were indicated, which led to a diagnosis of maculopathy, and treatment and prognosis were then presented. Recommendations were made.

Keywords : Maculopathy; chloroquine.

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