Abstract

SANTANA ALAS, Eva R et al. Fundus autofluorescence in patients with central serous chorioretinopathy. Rev Cubana Oftalmol [online]. 2010, vol.23, suppl.2, pp. 770-780. ISSN 0864-2176.

OBJECTIVES: To describe the peculiarities of the Fundus Autofluorecense in patiens with Central Serous Chorioretinopathy (CSC), and determine the relationship with functional and anatomic disturbances of the macular region. METHODS: Cross-sectional descriptive study performed in 21 eyes (21 patients), suffering from central serous chorioretinopathy in different statings. The pattern of autofluorecense in the neurosensoral detachment was detected with the Heidelberg´s Retinal Angiograph (HRA2) on 30° position. The optical coherence tomography (3D-OCT-Topcon) (Nidek) measured the central macular thickness and exposed the anatomic changes. Flourescein angiografy with HRA2 was performed on 12 patients. RESULTS: Hypoautofluorescense was detected in 51,90 % and hyperautofluorescense in 42,86 % of cases respectively; both disorders were present in 4,76 % of the patients. There was no significant difference between hyperautofluorecense and hypoautofluorescense as to the best corrected visual acuity (mean of 0,43 and 0,49, respectively; p= 0.184), and the central macular thickness (mean of 371.3 µm and 388.1 µm, respectively; p= 0.867). However, the difference was significant between time of evolution and the pattern of autoflorescence (p= 0.023). In those eyes affected by hyperautofluorescense, the optical coherence tomography allowed observing irregularities on the external layers and on the retinal pigmentary epithelium. The 83,3 % of cases who needed AGF presented with hyperautofluorescense that matched with hypoautofluorescence in the leakage site. CONCLUSIONS: In the central serous chorioretinopathy, different autofluorescense patterns may be found that reflect changes in the external retina and the retinal pigmentary epithelium. The autofluorescense may help to identify the focal diffusion site.

Keywords : Central serous corioretinopathy; retinal pigmentary epitelium; fundus autofluorescense; optical coherence tomography; flourescein angiography.

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