Abstract

MIJAIL TIRADO MARTINEZ, Oslay  and  HERNANDEZ PEREZ, Arianna. Use of mitomycin-C in prevention of corneal haze. Rev Cubana Oftalmol [online]. 2011, vol.24, n.1, pp. 100-110. ISSN 0864-2176.

OBJECTIVES: To assess the visual results and the appearance of haze in patients underwent LASEK with intraoperative mitomycin-c. METHODS: A prospective and longitudinal and cases series type was conducted in the service of refractive surgery of the "Ramón Pando Ferrer" Cuban Institute of Ophthalmology in patients operated on between September and December, 2008 and with a 12 months follow-up. Sample included 92 eyes with myopia or myopic astigmatism. The visual acuity with and without correction, as well as the pre- and postoperative manifest refraction were analyzed. The corneal haze was quantified and the effectiveness, safety, prediction rates and stability were determined. Authors used the descriptive statistic techniques for the result analysis. RESULTS: The mean age was of 30.11 ± 7.00 years. The female sex accounted for the 58.82 %. The mean preoperative visual acuity without correction was of 0.12 ± 0.07 and the better corrected visual acuity was of 0.89 ± 0.15. A year after operated on the better visual acuity without correction and the corrected one were of 0.9 ± 0,01 (R: 0.5 to 1,0). The corneal haze grade 1 appears in two eyes (2.17 %). The effectiveness rate was of 1,01; the safety rate was of 1.02; the prediction was of 90.22 % of eyes in ± 0.50 dioptres. There was stability of refraction after the third postoperative month. CONCLUSIONS: There was improvement of visual acuity without correction in the postoperative period with maintenance of the preoperative corrected better visual acuity. The appearance of corneal haze was minimal. The effectiveness, safety, prediction and stability rates showed values similar to international standards.

Keywords : Subepithelial keratomileusis; procedure; mitomycin-C; therapeutical use.

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