Abstract

FERNANDEZ-GONZALEZ, Loreto; BRAVO VALENZUELA, Paulina; RUSSO NAMIAS, Moises  and  SEPULVEDA, Dino. Implementation of clinical trials and post-trial access to COVID-19 vaccines in Latin America. Rev Cub Sal Públ [online]. 2022, vol.48, n.2  Epub June 01, 2022. ISSN 1561-3127.

Latin America was during November 2020 one of the most affected regions by the COVID-19 pandemic in terms of prevalence and deaths attributed to the virus. Therefore, the start of vaccine testing in citizens of the region was received with high expectations about its effectiveness. Therefore, it is essential to take into account certain fundamental principles that should guide this process ensuring its correct implementation. The objective of this article is to provide considerations on the process of implementing clinical trials and post-trial access to COVID-19 vaccines in Latin America, in particular those related to respect for the dignity of participants, the historical global and regional tensions regarding the political economy of clinical trials, some aspects of global governance and the role of the World Health Organization in the pandemic, and the need to ensure post-trial access to the vaccine. It is concluded that the pandemic is an opportunity to strengthen bonds of cooperation and solidarity between Latin American countries. Clinical trials are a key instance to strengthen local and regional governance with a view to consolidate transparency and monitoring of the correct implementation of public-private partnerships in the development of therapies, in which the World Health Organization and the Pan American Health Organization have an important role for the implementation of integration strategies and access to vaccines.

Keywords : vaccines; clinical trial; COVID-19 vaccine; research ethics.