Abstract

PEREZ CABARCO, Nancy  and  PEREZ CABARCO, Laura. Proceding of Fibrinogen Levels in Blood Donors Subjectd to a Plasmaferesis Program. AMC [online]. 1999, vol.3, n.4, pp. 0-0. ISSN 1025-0255.

An experimetal, longitudinal and prospective study is carried out in 16 blood donors RH negative, subjected to soft plasmaferesis program with the aim of determining fibrinogen levels at a plasmapheresis time, as well as 15 days after being performed, and also value if risings ocurred, which may limit the follow­up with the frecuency and quantity established . Patients were grouped as to number of plasmapheresis performed. Results of fibrinogen levels of second determination were compared with results of first one, as well as with results of one control group composed of 32 donors non­subjectec to plasmapheresis regimen. Results shoved that all determinations, not only of the control group but also of the study one, reached normal figures of 1, 5 to 4 gm/L, stadistic differences highly significant were found in the study group among the first and second determination of plasmatic fibrinogen and significant in the last one with the control group? so it is inferred that after two weeks of performing plasmapheris, deficit is not restored in donors yet. The non­significant difference when comparing means of the first determination of the study group in relation with the control one forced us to consider the period equal or longer than four weeks post­plasmapheresis sufficient for compensating physiological losses of fibrinogen. The abnormal increasing of fibrinogemia in donors with plasmapheresis was not detected, and values within normal limits were obtained in oll samples.

Keywords : BLOOD DONORS; PLASMAPHERESIS; FIBRINOGEN.

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