Background:

malignant melanoma is an invasive tumour and difficult to treat due to its high level of mortality and aggressiveness, a morphometry study was required to provide a proper diagnosis of the disease.

Objective:

to describe the behavior of morphometric indicators as nuclear area, nuclear volume and nuclear shape factor.

Methods:

a case series study in 12 patients having malignant skin melanoma was carried out, in the period from September 2015 to September 2017 in Holguin Province. Theoretical and empirical methods were used; these last two methods were based on Morphometric techniques. Then a statistical analysis of the information obtained was performed and they were added on a chart.

Results:

the area and nuclear volume showed low rate. The shape factor showed less levels of pleomorfism than the ones described in specialized literature.

Conclusions:

when low values of nuclear volume and nuclear area in malignant melanoma are found we are dealing with hyperplastic tissue. The same happens with the incidence of the nuclear area; the values of the nuclear shape factor evidenced less pleomorfi levels than the ones described in specialized literature.

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