Abstract

DELGADO, Livan; VAZQUEZ, Ana M  and  FERNANDEZ, Eduardo. Immunotherapeotical alternatives for the atherosclerosis treatment. Vaccimonitor [online]. 2012, vol.21, n.1, pp. 38-42. ISSN 1025-028X.

Atherosclerosis represents the first cause of death in the western world. Although there are several hypothesis which explain its pathogenesis, one of the most recognized is the autoimmune hypothesis. The activation of the immunological system against different atherogenic stimulus induces a reaction which may affect the vascular endothelium with the consequent atherogenic lesion development. The design of new therapeutic strategies, among them vaccines, represents a tool with promissory result in atherosclerosis treatment. Taking into account these antecedents, in the present work it was examined the state of the art on the immunomodulation of this chronic disease.

Keywords : Atherosclerosis; immunotherapy; vaccine; antigens; antibodies.

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