Abstract

RAYA GONZALEZ, David et al. Toxicological study of an aqueous extract from Enterolobium cyclocarpum (Jacq.) Griseb. duramen. Rev Cubana Plant Med [online]. 2008, vol.13, n.3, pp. 0-0. ISSN 1028-4796.

Rationale: A protective effect of the aqueous extract from Enterolobium cyclocarpum (Jacq.) Griseb duramen on pinewood was reported. It was also attributed anti-nutritional and repellent action against dry wood termites Incisitermes marginipennis (Latreillé); it is considered a potential candidate for perishable dry wood preservation, whose possible toxicity must be studied. Objectives: To determine the toxicity of aqueous extract from E. cyclocarpum duramen. Methods: Mean inhibitory and lethal concentrations (IC₅₀/LC₅₀) of an aqueous extract from E. cyclocarpum duramen in organisms from different trophic levels. Results: LC₅₀ for Artemia salina crustacean, I. marginipennis termite and Wistar rat were 1,3; 2 mg/mL and over 2 000 mg/kg_ind respectively. In microbial isolates, IC₅₀ was 300 mg. In MCF-7 tumor cell line, IC₅₀ was 1,3 mg. Conclusions: When comparing observed IC₅₀/LC₅₀ with allowable toxicity limits, it was concluded that the extract under study was not toxic for these organisms.

Keywords : IC₅₀/LC₅₀; crustacean; termite; rat; bacteria; fungus; oomicet; MCF-7 cells.

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