Abstract

DOMINGUEZ CARDOSA, Magda Corina et al. Levels of autoimmune response by antinuclear antibodies in patients with viral infections. MEDISAN [online]. 2012, vol.16, n.11, pp. 1753-1760. ISSN 1029-3019.

A descriptive observational and immunological study was carried out in 42 patients with diagnosis of autoimmune disease or suspicion of this, attended at the Immunology Department of "Saturnino Lora Torres" Provincial Clinical Surgical Teaching Hospital of Santiago de Cuba, from March 2010 to May 2011, who presented with viral hepatitis or other infections, in order to demonstrate the possible association between the clinical entity and viruses. Other serums of members of renal transplantation plan, belonging to histocompatibility studies, were used because of their high incidence of hepatitis B or C (or both), and levels of autoantibodies were determined by means of the immunodiagnosis method to detect antinuclear antibodies of the indirect immunofluorescence (qualitatively), so that the influence of viruses could be identified in autoimmune processes and, simultaneously, to recover the use of this technique. The results showed 28% of antinuclear antibodies-positive cases

Keywords : autoimmune response; antinuclear antibodies; viral hepatitis, virus; indirect immunoflourescence technique; Immunology Department; secondary health care.

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