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MEDISAN
On-line version ISSN 1029-3019
Abstract
MOREJON GARCIA, Moisés. Prescription of new antifungal drugs in patients with invasive candidiasis. MEDISAN [online]. 2014, vol.18, n.9, pp. 1316-1321. ISSN 1029-3019.
The invasive fungal infections have reached such an important dissemination in the intensive care units that today they constitute the fourth cause of acquired infections in this service, with a mortality of up to 50%. The immunodepression characteristic of the patient in critical state, together to the application of certain traumatic procedures -- catheters, probes, endoscopies, ventilation, abdominal surgical interventions, parenteral nutrition, among other --, predispose to the infection. In this respect, a range of new antifungal drugs are being used (triazoles and equiniocandines) in the treatment of patients with invasive mycosis, on the base that the creation of therapeutic protocols can decrease the mortality index caused by these disorders
Keywords : invasive candidiasis; fungal infections; antifungal drugs; triazoles; equinocandines.