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Medicentro Electrónica
On-line version ISSN 1029-3043
Abstract
GIL GUIRADO, Liliyisel et al. Fibrosis indices in non-alcoholic fatty liver disease follow-up. Medicentro Electrónica [online]. 2023, vol.27, n.3 Epub Sep 01, 2023. ISSN 1029-3043.
Introduction:
non-alcoholic fatty liver disease is a clinical and morphological condition characterized by fatty infiltration of the liver in more than 5%; it has two stages: simple steatosis and steatohepatitis, which can progress to fibrosis, cirrhosis and hepatocellular carcinoma.
Objective:
to determine the relationship between clinical and epidemiological variables with this disease, as well as fibrosis indices and their relationship.
Methods:
a cross-sectional descriptive study was carried out in patients seen in the liver and biliary tract consultation at " Dr. Celestino Hernández Robau" University Hospital from January to December 2017. We worked with a population made up of 60 overweight or obese patients older than or equal to 20 years who were diagnosed with primary non-alcoholic fatty liver disease.
Results:
the age group between 50-59 years of age, female gender, obese ones and with grade I steatosis prevailed. We found that 73.33% of the patients had metabolic syndrome and grade II steatosis prevailed in them. A number of 28 patients were found with indeterminate and high risk in the FIB-4 and NAFLD classifications, respectively, when relating the risks of fibrosis, as well as 5 had high risk in both variables. The FIB-4 and NAFLD indices had a significant, directly proportional, and considerable correlation.
Conclusions:
the correlation detected between the FIB-4 and NAFLD indices reaffirmed the value in the detection of suspected fibrosis and guided, in clinical practice, the conduct of different patients with this condition.
Keywords : non-alcoholic fatty liver disease; metabolic syndrome.