Abstract

ALVAREZ PANEQUE, Osmany et al. Clinical Evaluation in Children with Allergic Rhinitis Treated with Montelukast. ccm [online]. 2016, vol.20, n.3, pp. 452-467. ISSN 1560-4381.

Introduction: Allergic rhinitis is an IgE-mediated inflammation of the nasal mucosa induced after allergen exposure and presents with the 3 cardinal symptoms of sneezing, nasal obstruction, and rhinorrhea. Allergic rhinitis is a global health problem and is increasing in prevalence. Objective: to evaluate the effectiveness of montelukast in children with persistent allergic rhinitis in the Rene Avila Reyes Polyclinic, in Holguín, from October 2012 to February 2013. Methods: a prospective analytical study was performed including 20 patients aged from 6 to 19 years old. The variables analyzed in the study were: sex, age, other allergicdiseases, nasal symptoms in the day, symptoms in the night, and ocular symptoms in the day and total eosinophils. For comparative analysis we used the McNemar test p=0.01. Results: 12 patients (60.0%) of male sex were found, 16 (80.0%) with Bronchial Asthma and 8 (40.0%) with atopic dermatitis. Before the treatment 20 patients had nasal itch, 16 had nasal obstruction and 1 patient had normal levels of eosinophils. After treatment with montelukast 1 patient (5.0%) had nasal itch and nasal obstruction and 3 patients had high levels of eosinophils. Conclusions: in the population had prevalence of male patients, adolescents and with Bronchial Asthma.  Montelukast was effective for managing and control of symptoms the patients with Allergic Rhinitis.

Keywords : allergic rhinitis; montelukast; leukotriene receptor antagonists; nasal mucosa.

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