Abstract

LOPEZ ARBOLAY, Omar; GONZALEZ GONZALEZ, Justo Luis; MORALES SABINA, Osmany  and  NEDEL VALDES, Lorenzo. Transsphenoidal surgery: first treatment option for GH secreting hypophyseal adenomas. Rev Cubana Endocrinol [online]. 2004, vol.15, n.3, pp. 0-0. ISSN 1561-2953.

The elevation of the growth hormone (GH) levels enhances the grotesque growth of acral parts (acromegaly) or the increase of height (gigantism) according to age, as well as metabolic disorders of biological relevance. The selective adenotomy is among the treatment modalities. The objective of the present paper was to evaluate the results of the microsurgical transseptosphenoidal treatment of the GH producing adenomas in our setting. A retrospective study of patients that underwent transseptosphenoidal surgery for presenting this variety of adenomas at the neurosurgery service of "Hermanos Ameijeiras" Hospital from 1996 to 2003, was conducted. Age, cardinal symptoms, imaging, hormonal levels, complications and evolution, were analyzed. Complications related to the surgical procedure were not significant and none of them persisted more than a month. Diabetes insipidus was the most frequent. The symptoms improved and the GH titers were under the cure levels in 58.06 % of the operated on. It was concluded that transseptosphenoidal adenotomy is a safe and recommendable procedure as an elective treatment in these patients

Keywords : Acromegaly; adenotomy; cure; gigantism; growth hormone (GH),; transseptosphenoidal.