Abstract

Hormone therapy and bone quality. Rev Cubana Endocrinol [online]. 2005, vol.16, n.2, pp. 0-0. ISSN 1561-2953.

Osteoporosis is recognized as one of the health problems of the female postmenopausic population and the replacement hormone therapy (RHT) as one of the effective therapeutical measures to prevent fracture. We proposed ourselves to show the experience accumulated in relation to the effect of the replacement hormone therapy on the bone quality. In a retrospective study conducted among 42 women aged 30-59 that attended the Climacteric and Osteoporosis Clinic and the multidisciplinary office of climacteric of “Ramón Gonzales Coro” Gynecoobstetric Hospital from January 1997 to December 2003, it was determined the bone quality by dual X-ray absorptiometry in the lumbar region (L2-L4) or by calcaneus ultrasound (CALUS). They receive continuing treatment with estrogenic therapy (E) or with progestogenous estrogens (PE) for no less than a year (n = 30). Women who were not able to receive RHT were grouped and evaluated as a control group (n = 12). During an average observation time of 2 years, the females that receieved RHT improved their bone quality in 16.8 %, whereas those of the control group got worse in 8 % of the cases. The initial results, although modest, showed the usefulness of RHT for improving the bone quality and the need to continue carrying out studies that allow to define in our setting the persistance of bone improvement, as well as the magnitude of postmenopausic osteoporosis.

Keywords : Menopausia; osteoporosis; hormone therapy; calcaneus ultrasound.

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