Abstract

BERMUDEZ ROJAS, Sergio et al. Glycemia and insulin action disturbances in diabetes-risk population. Rev Cubana Endocrinol [online]. 2009, vol.20, n.3, pp. 120-130. ISSN 1561-2953.

OBJECTIVE: to know the hyperglycemia frequency and resistance to insulin in a group of patients with risk of carbohydrates metabolism disturbances. METHODS: a cross-sectional and descriptive study was conducted in a population from the Reina polyclinic. A total of 118 patients were studied to measure the fast and postprandial glycemia after an oral load of glucose e insulinemia. For insulin-resistance calculus HOMA-IR index was applied. RESULTS: there was a 5.1 % of diabetic patients aged over 60 and hypertensive; 25.4 % of sample showed some degree of hyperglycemia in the pre-diabetes rank. Glycemia disturbances increased in a parallel way to age increase (p= 0.005). Insulin-resistance was detected in 21,2 % of total of included patients and in 53.8 % of those presenting with some hydrocarbon metabolism disturbance being more marked in diabetic patients affecting to 83.3 % (p= 0.001). CONCLUSIONS: hyperglycemia-associated disturbances and insulin-resistance associated with hyperglycemia are frequent in clinical practice when risk group are studied due to diabetes.

Keywords : prediabetes; fast dysglycemia; altered glucose tolerance; insulin-resistance.

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