Abstract

CABRERA GAMEZ, Maité et al. Results of somatotropinoma surgery through endoscopic transnasal approach using the neuronavigation technique. Rev Cubana Endocrinol [online]. 2014, vol.25, n.2, pp. 66-75. ISSN 1561-2953.

Introduction: treatment of choice for growth hormone-producing hypophysial tumors is surgery. The recurrence percentage is high but, to a great extent, is related to the surgeon´s experience, the surgical technique and the multidisciplinary work. Since 2011, a multidisciplinary team was created to guide the behavior and the follow-up of these patients who would be operated on by using the endoscopic technique based on the neuronavigation. Objective: to describe the results of the growth hormone-producing hypophysial adenomas surgery by using the neuronavigation technique. Methods: a descriptive study that included checking of the medical records of 18 patients diagnosed with growth hormone-producing hypophysial tumors and referred for endoscopic surgical treatment through neuronavigation. The analyzed variables were age, sex, tolerance test for glucose to measure growth hormone before and 7 days after surgery, the characteristics of the tumor, the postsurgical complications and the progress. Results: of this group of 18 patients, 66.6 % were males 33.4 % had tumors growing into the floor of the Turkish saddle and the postsurgical complications were minimal: 16.7 % presented with transient diabetes insipidus and the same percentage had a cerebrospinal fluid fistula. Biochemical remission was detected in 55 % of patients one week after the surgery. Conclusions: growth hormone-producing hypophysial tumors surgery using the endoscopic technique with neuronavigator provides advantages for patients, with satisfactory recovery from the clinical and biochemical viewpoint as well as low frequency of complications.

Keywords : growth hormone-producing hypophysial adenomas; hypophysial tumor surgery; neuronavigation technique.

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