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Revista Cubana de Endocrinología
On-line version ISSN 1561-2953
Abstract
VALDES RAMOS, Eduardo R.; VALDES BENCOSME, Eduardo R. and VALDES BENCOSME, Niurka N.. Risk Factors Associated with Cardiovascular Complications in Middle-Aged Women with Type 2 Diabetes Mellitus. Rev Cubana Endocrinol [online]. 2020, vol.31, n.2 Epub Nov 06, 2020. ISSN 1561-2953.
Introduction:
In middle-aged diabetic women, a series of atherogenic factors converge that favor the appearance of cardiovascular complications.
Objective:
To identify the risk factors associated with cardiovascular complications in middle-aged women with type 2 diabetes mellitus.
Methods:
An analytical case-control study was carried out with middle-aged (40-49 years old) women with type 2 diabetes and who were admitted to the Diabetic Care Center in Bayamo City, Granma, from 2010 to 2017. Women with artificial menopause were not part of the study. The sample was made up of 375 patients, who were selected by simple randomized sampling: 125 presented cardiovascular complications (cases) and 250 presented no complications (controls).
Results:
The number of women with cardiovascular complications was correspondingly higher with menopause and with the time after the occurrence of this event (p = 0.0125). Univariate analysis showed that seven factors increased the risk for presenting cardiovascular complications, among them menopause (OR = 1.88, CI: 1.1-3.0, p = 0.0077); while multivariate analysis showed that only three of them did so independently, which were time of evolution of diabetes over ten years (OR = 4.97, CI: 2.35-10.54, p = 0.000), arterial hypertension (OR = 3.58, CI: 1.71-7.48, p = 0.001), and smoking (OR=2.605, CI: 1.47-4.59, p = 0.001).
Conclusions:
The main risk factors associated with cardiovascular complications among middle-aged women with type 2 diabetes mellitus were time of evolution of diabetes over ten years, arterial hypertension, and smoking.
Keywords : type 2 diabetes mellitus; cardiovascular diseases; menopause; middle age.