Abstract

RUFIN GOMEZ, Lorenzo Ángel; RUFIN BERGADO, Ana Margarita; MARTINEZ MOREJON, Amancio  and  VEGA SOCORRO, Martha Noraida. Glucide metabolism disorders and metabolic syndrome in COVID-19 patients. Rev.Med.Electrón. [online]. 2021, vol.43, n.5, pp. 1395-1408.  Epub Oct 31, 2021. ISSN 1684-1824.

Metabolic syndrome includes a set of cardiovascular risk factors associated with resistance to insulin, favoring the appearance of cardiovascular disease and diabetes mellitus type 2. Its etiology is attributed to the combination of genetic and environmental factors, associated to lifestyle, and favoring a proinflammatory and prothrombotic status that worsens the clinical characteristics of the patients with COVID-19. The objective of the review was to analyze the current state of the scientific knowledge in research on the interrelationship between glucide metabolism disorders and metabolic syndrome, associated with the exacerbated proinflammatory condition in COVID-19 patients. Searches were conducted in PubMed, SciELO, CinicalKey, and LILACS databases. A relevant role in the metabolic syndrome pathogenesis is attributed to the inflammatory process generated by poor eating habits, high caloric overfeeding, and to sedentary lifestyle, and also to possible complications with associated comorbidities in COVID-19 patients. It is possible to reduce the metabolic syndrome inflammatory condition through life style and alimentary habits changes that prevent obesity and its effects on insulin resistance and propitiate the reduction of the disease severity associated with the inherent inflammatory processes.

Keywords : metabolic syndrome; obesity; resistance to insulin: fructose; inflammation; COVID-19.

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