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Revista Médica Electrónica
On-line version ISSN 1684-1824
Abstract
LINARES-MORERA, Anmy et al. Lipid markers in HIV AIDS patients under treatment with protease inhibitors. Rev.Med.Electrón. [online]. 2023, vol.45, n.5, pp. 845-858. Epub Oct 31, 2023. ISSN 1684-1824.
Introduction:
Cardiovascular diseases are the main risk of morbidity and mortality worldwide. Another disease with significant impact on public health systems is HIV/AIDS. Patients infected with the human immunodeficiency virus have a higher risk of developing cardiovascular diseases. After antiretroviral treatment, the incidence of opportunistic diseases associated with HIV/AIDS has decreased and the incidence of diseases associated with aging such as cardiovascular disease has increased. The use of protease inhibitor antiretroviral drugs is associated with hyperlipidemia and a consequent increase in cardiovascular complications.
Objective:
To determine lipid markers in patients with HIV/AIDS undergoing treatment with protease inhibitors.
Materials and method:
An observational, analytical, cross-sectional study was carried out in patients with HIV/AIDS from the province of Matanzas during the period from March to August 2020, in the Clinical Laboratory of the Provincial Teaching Clinical Surgical Hospital Faustino Pérez Hernandez.
Results:
Lipid markers were evaluated as cardiovascular risk factor associated with antiretroviral treatment, with triglycerides being the one of highest incidence.
Conclusions:
Lipid markers were identified as cardiovascular risk factors; in this case hypertriglyceridemia.
Keywords : cardiovascular disease; HIV; AIDS; antiretroviral drugs; cardiovascular risk factors.