Abstract

POZO ROMERO, José Antonio; FERNANDEZ RAMOS, Humberto; CORREA BORRELL, Mayda  and  CARBALLO, José Fabio. Comportamiento hidroelectrolitico y acidobásico con el empleo de soluciones salinas ligeramente hipertonicas en neurocirugía. Rev cuba anestesiol reanim [online]. 2010, vol.9, n.1, pp. 48-54. ISSN 1726-6718.

Introduction: Use of normal saline solution slightly hypertonic regarding the plasma, may to increase the osmotic gradient and to reduce the presence of fluids in solid organs (brain, liver, heart, kidneys) but also may to produce alterations in hydroelectrolytic and acid-base balance. Objective: To determine the hydroelectrolytic and acid-base behavior related to use of saline solutions with different tonicity degree. Material and Method: A cross-sectional, observational and comparative study was conducted in 24 patients underwent elective intracranial surgery from January to June, 2009 in "Manuel Ascunce Domenech" Hospital of Camagüey province. In the first patient as maintenance solution we used 0,9% sodium chloride, in the second one 1.1% sodium chloride and in the third we used 1.3% saline solution; in all patients the same neuroanesthesia technique was applied. Variables used included the serum electrolytes determinations of sodium, potassium and chlorine, plasma osmolarity, pH, PaCO2 and standard bicarbonate. Results are expressed in table. Results: Serum osmolarity and restrained electrolytes remained within the normal parameters in most of patients. Respiratory alkalosis present hasn't relation to the use of sodium chloride solutions, but the hyperventilation. Conclusions: With use of the three solutions there weren't significant disturbances of hydroelectrolytic and acid-base equilibrium in most of patients.

Keywords : Hypertonic saline solution in neuroanesthesia.

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