Abstract

FERNANDEZ MESA, Teresita de los Ángeles et al. Diagnostic significance of antinuclear antibodies. Rev Cuba Reumatol [online]. 2016, vol.18, suppl.1, pp. 0-0. ISSN 1817-5996.

Abstract Antinuclear antibodies present in the serum of patients with rheumatic diseases origin, such as Systemic Lupus Erythematosus, Sjögren's syndrome, Progressive Systemic Sclerosis and Polymyositis. In 1948, they discovered the lupus Erythematosus cell and its relationship with Systemic Lupus Erythematosus, pointing to the autoimmune nature of the disease, by demonstrating the existence of substances that autoantibodies call. Testing antinuclear antibodies are very useful in the study of autoimmune connective tissue diseases. Each has a private collection of antibodies that help, in some cases, be able to establish the diagnosis, in others point the prognosis of the disease. There proteins is very important, and it constitutes a valuable tool like marker inflammatory in rheumatologic illnesses of immunological origin

Keywords : Antinuclear antibodies; rheumatologic illnesses; Indirect Immunofluorescence.

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