Abstract

ALVAREZ LOPEZ, Alejandro; FUENTES-VEJAR, Rodrigo; SOTO-CARRASCO, Sergio Ricardo  and  GARCIA LORENZO, Yenima de la Caridad. Prolotherapy in knee osteoarthritis. Rev Cuba Reumatol [online]. 2021, vol.23, n.2  Epub Aug 01, 2021. ISSN 1817-5996.

Gonarthrosis is a very frequent entity and affects a large group of patients especially above 40 years, conservative treatment is the first line and includes prolotherapy. To update knowledge regarding the use of prolotherapy in patients with gonarthrosis. The information was searched and analyzed over a period of two months (February 1, 2020 to April 30, 2020) and the following words were used: prolotherapy, regenerative injection therapy and chronic musculoskeletal pain. Based on the information obtained, a bibliographic review of a total of 203 articles published in the PubMed, Hinari, SciELO and Medline databases was carried out using the search manager and reference manager EndNote, 39 selected citations were used to make the review, including 32 of the last five years, also consulted a book. The concentrations to be used both intra and periarticular, indications and mechanisms of action are mentioned. The frequency of its application is described, as well as the comparison with other intra-articular treatment methods. Reference is made to the duration of its effect and complications. Prolotherapy by administering intra-articular hypertonic dextrose is a useful method in the treatment of patients with gonarthrosis, its easy application, availability and low complication rate make it a feasible and effective conservative method.

Keywords : prolotherapy; gonarthrosis; knee osteoarthritis; conservative treatment.

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