Abstract

ARTECHE PRIOR, Marianela et al. Brain nocardiosis: presentation of a case. Rev. CENIC Cienc. Biol [online]. 2020, vol.51, n.1, pp. 84-91.  Epub Apr 01, 2020. ISSN 2221-2450.

The bacteria of the genus Nocardia are Gram positive, aerobic, partially acid resistant microorganisms, which in most cases are acquired by inhalation or inoculation through the skin. Hematic dissemination can compromise the Central Nervous System in the form of intra-parenchymal abscesses. Cerebral nocardiosis is a rare condition, it represents 2% of brain abscesses, is usually present in immunocompromised patients and is very rare in immunocompetent patients. It evolves with significant morbidity and mortality. The objective of this work was to characterize a patient with general and neurological symptoms as a form of presentation of a Nocardiosis with involvement at the cerebral vascular level. The case of a 59 year old patient is presented, with vascular risk factors such as hypertension, diabetes mellitus, left carotid atheromatosis demonstrated by Doppler of the Supra Aortic Trunks and a history of harmful toxic habits such as excessive alcohol intake, and malnutrition, In addition, presenting a general syndrome associated with a picture of focal neurological deficit and respiratory and abdominal manifestations, several diseases were suspected such as cerebral tuberculosis, neurosyphilis and other sepsis due to opportunistic and atypical germs that cause secondary vasculitis the possibility of encephalitis or lymphoma secondary to HIV infection was also considered. It is concluded that our patient was characterized as a carrier of a non-atherosclerotic cerebral vascular occlusion in the course of a systemic infection by asteroid Nocardia associated with an immunodeficiency secondary to chronic liver disease and the recommended antimicrobial treatment for this disease was satisfactory.

Keywords : cerebral Nocardiosis; nocardia infection; central nervous system; antimicrobial treatment.

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