Abstract

RODRIGUEZ CARDENAS, Antonio  and  VELAZCO BOZA, Alejandro. Use of 800 mg of Misoprostol to induce early abortion. Rev Cubana Obstet Ginecol [online]. 2003, vol.29, n.2, pp. 0-0. ISSN 1561-3062.

Misoprostol is similar to prostaglandins with uterotonic properties. A group of 141 patients with gestational time under 70 days received 3 doses of 800 mg of Misoprostol every 48 hours. Failure was defined by the need of performing a surgical abortion and success by the complete removal of the outcome. Generally speaking, 132 cases (93,6%) had normal abortion, 9 cases failed for 6,4%. The decrease in hemoglobin rates was statistically significant (p=0,001) but without clinical impact, before treatment: 11,9 mg/dL with standard deviation=1,19 and after treatment: 11,1 with a SD=1,20. There were no statistically significant differences among success rates and failure rates in relation to parity, pregnancy, previous abortions, race or age, but they were found in pregnancies over 9 weeks (p=0,01). The third dose of Misoprostol showed very low efficiency. The benefits that the reduction of treatment time plus the use of more frequent doses of this medicine, combined with different ways of administration, might bring are under research.

Keywords : MISOPROSTOL [therapeutic use]; ABORTION, INDUCED [methods].