Abstract

SANCHEZ LOMBANA, Rita et al. Toxoplasmosis and pregnancy. Rev Cubana Obstet Ginecol [online]. 2012, vol.38, n.1, pp. 99-106. ISSN 0138-600X.

Introduction: The toxoplasmosis is a zoonosis involving a third of world population. It is associated with congenital infections and abortion. Objective: To describe a clinical case of a patient presenting with toxoplasmosis associated with pregnancy. Methods: Patient aged 36 who at 21 weeks of pregnancy is assessed by the Provincial Genetics Department of La Habana by determination of IgM for positive toxoplasmosis. IgG and IgM determinations were performed and polymerase chain reaction (PCR) in amniotic fluid for Toxoplasm, which was positive. The couple received genetic advice and started a specific treatment. At 32 weeks is admitted in our service diagnosed with preterm delivery threat. A cesarean section of corporeal segment was carried out as well as surgical sterilization with a diagnosis of acute fetal suffering. Results: The conception was a male newborn weighing 1 800 g, a 9/9 Apgar scale. The newborn receive treatment with sulfadiazine, pirimetamine and folinic acid. Later, IgE and IgM determinations were made being negatives. She is discharged at 42 days weighing 2 520 g, a favorable evolution and ophthalmic assessment. Serologic follow-up of newborn was prescribed. Conclusions: Transmission rate in the seroconversion increases by week of gestational age, thus it is necessary to start an early therapy to avoid the complications and to carry out the long-term follow-up of these newborns to assess the disease prognosis.

Keywords : toxoplasmosis; Toxoplasma gondii; zoonosis; pregnancy; threat of preterm delivery; congenital infection.

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