Abstract

WONG NAVARRO, Roberto; FERNANDEZ-BRITTO RODRIGUEZ, José E; CONTRERAS BARRIONUEVO, Daniel  and  GUSKI, Hans. Aterosclerosis en edades tempranas de la vida: Estudio patomorfológico y morfométrico aplicando el sistema aterométrico. Rev Cubana Invest Bioméd [online]. 1998, vol.17, n.2, pp. 179-184. ISSN 1561-3011.

A study was made on the atherosclerotic lesions of 50 aortas from dead people under 35 years whose causes of death were not related to atherosclerosis. The deceased were divided into 3 groups by age and sex. The aortas were divided into thoracic and abdominal segments to be analyzed by the classical pathomorphological method. The morphometric analysis was carried ot using the atherometric system. The statistical operations were performed assisted by the commercial Number Cruncher Statistical System software. The most important results were the following: 1) the atherosclerotic lesions in both segments increase with rising age level and they are more intense in the abdominal segment; 2) the fatty streak (X) were observed in the aorta thoracic segment since 5 years of age whereas fibrous plaques (Y) occured at 16 years of age or over but in the abdominal segment. The statistical comparison test applied to age groups was significant in I-III groups and I-II groups, which suggest that during the second decade of life the development and progression of atherosclerotic lesions are stabilized. The atherometric system was the best tool for the study of atherosclerotic lesions in early stages of life.

Keywords : ATHEROSCLEROSIS [pathology]; AORTA, ABDOMINAL [pathology]; AORTA, THORACIC [pathology]; AUTOPSY.

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