Abstract

CABRERA LLANO, Jorge; CASTELLANOS GONZALEZ, Maricel  and  HIDALGO CALCINES, Pedro. C. Separación de hemoglobina A₂ y hemoglobina C por cromatografía en carboximetilcelulosa (CM-52) con amortiguador imidazol-HCl-KCN-NaCl. Rev Cubana Invest Bioméd [online]. 1998, vol.17, n.3, pp. 234-239. ISSN 1561-3011.

A new macrochromatographic technique was assayed in carboxymethylcellulose and damperer iminazole-HCL-KCN-NaCL at 6,7 pH. This technique es reliable and exact for A₂ hemoglobin separation and quantization in individuals carrier of AC hemoglobin, C Beta-thalasseamia, AS hemoglobin, and SC hemoglobin, whick, in many cases es of clinical interest. Also, a variant of A₂ hemoglobin was detected in a pregnant woman carrier of AC hemoglobin, and a Beta-thalassemic gen in Cis with the gen for C hemoglobin.

Keywords : CHROMATOGRAPHY [methods]; HEMOGLOBIN A₂ [analysis]; HEMOGLOBIN C [analysis].

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