Abstract

ZUMAETA VILLENA, Eduardo; GONZALEZ GRIEGO, Antonio; RAMIREZ ALBAJES, Victoria  and  FIGUEROA BARRIOS, Rolando. Inmunogenicidad de la vacuna recombinante cubana contra la hepatitis B en trabajadores de la salud peruanos. Rev Cubana Invest Bioméd [online]. 2000, vol.19, n.1, pp. 45-50. ISSN 1561-3011.

We researched into the immunogenicity (seroconversion, hyperesponse and geometric mean) caused by the Cuban recombinant anti-B viral hepatitis in Cuba in a national concurrent multicenter study. The 0, 1 and 2 month immunization schedule was used in 211 sensitive health workers who worked for the Peruvian Institute of Social Security. The immunoenzymatic method called Organon Teknika. 97% seroprotection was reached just in 75 days after the vaccination schedule started; higher immunogenicity was observed in under 40 years-old women. We recommended the implementation of this schedule as part of the control program of B hepatitis because of its simetry, short latency and level of protection

Keywords : VACCINES,SYNTHETIC [immunology]; VACCINES SYNTHETIC [administration and dosage]; HEPATITIS B VACCINES [administration and dosage]; HEALTH PERSONNEL; PERU.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )