Abstract

CLAPES, Sonia et al. Peroxidación lipídica y otros indicadores de estrés oxidativo en pacientes diabéticos. Rev Cubana Invest Bioméd [online]. 2001, vol.20, n.2, pp. 93-98. ISSN 1561-3011.

An important relationship between the levels of lipid peroxidation and the development of complications was observed in diabetes mellitus, a disease of endocrine origin. Variations were found in the concentration of products of lipid peroxidation (malondialdehyde) with values of 8.33 ± 2.90 in diabetic patients versus 4.51 ± 1.40 in sound individuals. The levels of reduced gluthatione, an endogenous antioxidant measured in serum of diabetic patients showed lower levels, 4.75 ± 2.31 and 8.30 ± 1.52 nmol/mL in serum of blood donors. It was found a significant reduction of catalase with values of 16.21 ± 18.25 versus 65.78 ± 24.78 U/mL. The decrease in the activity of superoxide dismutase was not remarkable

Keywords : LIPID PEROXIDATION; DIABETES MELLITUS [complications]; DIABETES MELLITUS [enzymology]; MALONDIALDEHYDE; OXIDATIVE STRESS; ANTIOXIDANTS [therapeutic use].

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )