Abstract

PARAPAR DE LA RIESTRA, José Mario  and  MOISES DANGUILLECOURT, Tamara. Morfometría de la corteza suprarrenal y de los valores séricos de sodio y potasio en ratas tratadas con Petiveria alliacea. Rev Cubana Invest Bioméd [online]. 2001, vol.20, n.2, pp. 113-117. ISSN 1561-3011.

For the therapeutic introduction of the total preparation of Petiveria alliacea it is necessary to prove the absence of harmful effects in endocrine organs as important as the suprarenal capsules that play an important role in the maintenance of arterial pressure and of the hydromineral balance. To accomplish these objects a morphometric study of the suprarenal cortex was conducted and the serum values of sodium and potasium in SHR rats of 3 months of age treated with a total preparation of Petiveria alliacea and in their respective controls were determined. It was observed a signifcant reduction in the size of the glomerular layer among the treated animals that could provoke a decrease of the levels of aldosterone in blood. The considerable increase of the suprarenal cortex in these animals may be connected with a rise in the secretion of cortisol, which may favor at the same time the renal function

Keywords : ADRENAL CORTEX [anatomy & histology]; RATS; INBRED SHR; ANIMALS, LABORATORY; HYPERTENSION [drug therapy]; PLANTS, MEDICINAL [therapeutic use]; SODIUM [blood]; POTASIUM [blood].

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