Abstract

CHAPLE LA HOZ, Manuel et al. Participación tubular renal en la génesis de la hipertensión arterial primaria. Rev Cubana Invest Bioméd [online]. 2003, vol.22, n.4, pp. 217-225. ISSN 1561-3011.

A sample of 45 essential hypertensive patients, 40 hypertensives and 40 healthy subjects aged 18-30 years, all males and classified according to the WHO criteria, was used to study the tubular role in primary blood hypertension. All of them were applied renal function tests and ultrasound among others. According to the results achieved, the pre-hypertensive young males showed a picture of tubular glomerular imbalance of glomerular predominance that explains the re-absorptive overload found, with rise in the evaluated renal volume. The low values of plasmatic creatinine clearing in the studied hypertensive young males, assuming that they were previously pre-hypertensive, determined a tubular glomerular imbalance with tubular predominance at present if the increase of tubular reabsorption of sodium and lithium, the decrease of Na+ excretion and the higher renal volume present in these persons are taken into consideration.

Keywords : HIPERTENSION; KIDNEY FUNCTION TEST; KIDNEY; HYPERTROPHY; SODIUM; LITHIUM.

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