Abstract

CRUZ MANZANO, Elio et al. Antioxidant state and indicators of oxidative damage in an elderly population in Las Tunas province. Rev Cubana Invest Bioméd [online]. 2004, vol.23, n.2, pp. 92-97. ISSN 1561-3011.

Twenty four men and twenty eight females aged 60 to 91 years were studied to evaluate the antioxidant status and the oxidative damage indicators of an elderly population in Las Tunas province. Concentration in blood serum of non enzymatic antioxidants such as vitamin A, b carotene, vitamin E, vitamin C, and zinc; the activity of antioxidant enzymes superoxide dismutase and catalase as well as concentration of indicators of oxidative damage, malondialdehyde and oxidized proteins were determined. Except for vitamin C and zinc for the whole population and the females respectively, the rest of antioxidant indicators are within the reported normal ranges. The states of Vitamin C and zinc are deficient in a high percentage of individuals whereas the activity of antioxidant enzymes is higher in older adults. However, the concentration of oxidative damage indicators are within the normal limits, which may indicate compensated oxidative stress

Keywords : Oxidative stress; elderly; vitamin A; carotene; vitamin E; vitamin C; superoxide dismutase; catalase; malondialdehyde; oxidized proteins.

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