Abstract

CANIZARES GRAUPERA, María Elena; RODRIGUEZ SOSA, Víctor Manuel; CARRAL NOVO, Juan Mariano  and  MCCOOK NOA, Leysis. Chemical and biological evaluation of different materials used as containers of surgical adhesives. Rev Cubana Invest Bioméd [online]. 2004, vol.23, n.4, pp. 253-258. ISSN 1561-3011.

Analytical chemistry methods were unified by using infrared spectroscopy and gravimetric evaluation of the materials before and after getting in touch with the adhesive. The results were statistically evaluated by analyzing the variance and using the t student test. The experiment was availed to evaluate the adhesion and histotoxicity in the treated tissue. The objective was to implement a sensitive and simple method to assess these interferences. According to the results, these materials are not useful for the container, since they all present a significant weight variation. It was concluded that the method is sensitive and adequate for further evaluations of other materials. The use of interdisciplinary techniques in the same experiment allows to integrate results and obtain more information with a minimum of lab animals. The result could be useful for the regulating toxicology, since there are no standing norms for this type of evaluation.

Keywords : Cyanoacrylates; adhesives; histotoxicity; containers.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )