Abstract

MORENO, Jorge Valdés; RODRIGUEZ DEL REY PINA, Orlando G  and  CARDELLA ROSALES, Lidia. Hepatitis C III. Laparoscopic and histological study and serum levels of alanine aminotransferase in 160 HCV seropositive patients. Rev Cubana Invest Bioméd [online]. 2005, vol.24, n.1, pp. 14-20. ISSN 1561-3011.

A laparoscopic and histological study was conducted and its correlation with the behavior of serum levels of alanine aminotransferase was determined in 160 HCV seropositive patients that were seen at the Outopatient Department of Gastroenterology of “Calixto García” Hospital from 1996 to 1998.  On the laparoscopic examination, it was observed that  37.5 % of the cases presented normal liver and that 37.7 % had hepatic steatosis. The rest of the studied patients had acute or chronic hepatitis (12.5 % in each case). On comparing the  histological studies and the serum values, it was found that among those patients that presented normal liver  in the morphological study, the values of alanine aminotransferase were equally distributed into normal and oscillating values; however, most of  the cases with chronic hepatitis (minimum, mild and moderate) showed  oscillating values of this enzime, and in the cases diagnosed as acute or chronic severe hepatitis, the alanine aminotransferase reached elevated values mantained in most of the  cases.The combination of the histological study and the determination of serum values of alanine aminotransferase proved to be the most effective way in the clinical assessment of the studied patients

Keywords : Viral infection; hepatitis C; hepatitis C virus.

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