Abstract

HERRERA BATISTA, Aleida; PULDON SEGUI, Giselle; DIAZ RONDON, Belsis  and  BACALLAO GALLESTEY, Jorge. Effects of chronic alcoholism on the arterial pressure and heart rate in male adolescent rats. Rev Cubana Invest Bioméd [online]. 2006, vol.25, n.1, pp. 0-0. ISSN 1561-3011.

The effects of chronic alcoholism initiated in the adolescence on arterial pressure and heart rate were characterized in male albine rats. They were divided into 2 groups (experimental and control) and 2 subgroups with different times of treatment (3 and 5 months) were organized. The experimental rats were administered ethanol by intraesophageal cannula. Arterial pressure and heart rate were studied by direct plethysmography. A two-way interactive ANOVA was used for the statistical processing of the results. The ingestion of ethanol produced an increase of the systolic and diastolic arterial pressure  at 3 and 5 months of treatment. This rise was higher at 5 months of treatment. Heart rate did not show significant changes. It was concluded that the chronic ingestion of ethanol raises arterial pressure depending on time.

Keywords : Chronic alcoholism; arterial hypertension; heart rate; adolescence; ethanol; rat.

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