Abstract

PITA RODRIGUEZ, Gisela et al. Levels of antioxidant vitamins in plasma from patients with myocardial infarction. Rev Cubana Invest Bioméd [online]. 2007, vol.26, n.1, pp. 0-0. ISSN 1561-3011.

The possible association between the deficient serum levels of vitamins E, C and A with the presence of myocardial infarction and smoking habit is evaluated. A sample composed of 34 patients with a first myocardial infarction was selected. The controls, 61 in all, were taken at random in the last month of every quarter. The serum levels of vitamins E, C and A were determined and a lipid profile was performed. The smoking habit was evaluated as a factor in the influence of vitamin concentrations and the history of arterial hypertension. 93.3 % of the cases and 59.3 % of the controls smoked once in their lives. The means of the plasmatic vitamin C values were significantly higher in the control compared with the cases (p< 0,001). It was not so with the values of vitamin A (retinol) and E (α tocoferol) found. The association of the myocardial infarction with the vitamin C deficiency was marked with OR =5.95 and CI =1.27 - 36.84. It was not observed a significant association with the deficiency of α tocoferol OR =1.89 CI=0.72 - 5.05. The analysis of the association between the vitamin C deficiency and the smoking habit was remarkable with p= 0.009, but the association of the α tocoferol deficiency with the smoking habit was not significant (p=0.691). No vitamin A deficiencies were detected.

Keywords : Antioxidant vitamins; myocardial infarction; vitmain C; vitamin E; vitamin A; serum lipids.