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Revista Cubana de Investigaciones Biomédicas

On-line version ISSN 1561-3011

Abstract

CRUZ ALVAREZ, Yainet; TOME LOPEZ, Orlando; SELVA SILVA, Selma  and  CRUZ GARCIA, María A.. Morphometric study of the organs of rats’ offsprings with retarded intrauterine growth. Rev Cubana Invest Bioméd [online]. 2007, vol.26, n.1, pp. 0-0. ISSN 1561-3011.

It was our objective to check the morphometry of some internal organs in rats’ offsprings with  retarded intrauterine growth by comparing them with a control group. The retarded intrauterine growth was induced by ligation of the uterine artery in both horns on the 16th day of gestation in Sprague Dawley rats. The offsprings are studied at birth, and on the 7th, 14th and 21st day. The weight and volume of the kidneys, liver, heart, lungs and intestine were verified. The weight and volume of the organs showed lower values compared with the control group in all the  times studied. It was observed that the reduction of the blood flow in the last week of pregnancy produced organic alterations in the examined offsprings that were maintained until weaning.

Keywords : Retarded intrauterine growth; organ morphometry; rats offsprings.

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